Gallbladder cancer occurs when cancer cells grow in your gallbladder. Your gallbladder is a pear-shaped organ in the upper right side of your abdomen, just below your liver. It stores and distributes bile, a fluid that your liver secretes to help digest the fats in your foods. Gallbladder cancer starts in the innermost layer of your gallbladder, called the mucosal layer, and spreads outward. It often does not cause signs or symptoms in the early stages. Instead, healthcare providers often discover cancer incidentally after gallbladder surgery.